Tiered Protocol for Sussing Out Endocrine Disruption

Tiered Protocol for Sussing Out Endocrine Disruption

A team of experts in biology, chemistry, and toxicology has developed a protocol to help industrial scientists detect endocrinedisrupting tendencies early in the chemical development process. What sets the Tiered Protocol for Endocrine Disruption (TiPED) apart from the protocols typically used to assess product safety is its incorporation of what the authors believe to be the best assays for de...

Designing Endocrine Disruption Out of the Next Generation of Chemicals.

A central goal of green chemistry is to avoid hazard in the design of new chemicals. This objective is best achieved when information about a chemical's potential hazardous effects is obtained as early in the design process as feasible. Endocrine disruption is a type of hazard that to date has been inadequately addressed by both industrial and regulatory science. To aid chemists in avoiding thi...

Impedance for Endocrine Disruption Compounds

An unintended consequence of our chemical innovations is the introduction of trace chemicals into our environment that are not necessarily directly toxic, but can impact nature. Mutations in animals/people can happen naturally, but perhaps in many cases human chemical ingenuity is to blame. Our motivations as chemists are honorable, and we have generated pesticides that help us to grow more foo...

Endocrine disruptors: from endocrine to metabolic disruption.

Synthetic chemicals currently used in a variety of industrial and agricultural applications are leading to widespread contamination of the environment. Even though the intended uses of pesticides, plasticizers, antimicrobials, and flame retardants are beneficial, effects on human health are a global concern. These so-called endocrine-disrupting chemicals (EDCs) can disrupt hormonal balance and ...

Endosulfan and Endocrine Disruption: